Wednesday, December 25, 2019

The War Against List of Concept Essay Topics

The War Against List of Concept Essay Topics Now you are aware that proposal essay has to be done utilizing the prescribed form. It is preferable to prevent topics that are overdone. Pick an intriguing essay topic, and you will begin enjoying it. Recent argumentative essay topics that are related to society is going to do. It's possible to also restate the ideas which you've discussed in the body paragraphs in order to make your point valid. Along with a good structure, you will want an argument, a strong thesis, and strong research. Clarify how you'll address your topic, identify sub-arguments you have to prove to create your large argument true. Since it's such a huge subject, you're going to want to narrow your paper down to a particular angle. As you probably know, simply because you've got a definition essay topic and a couple examples doesn't signify you've got an essay. Your essay might think about the ways a definition of friendship evolves as an individual gets older, and you may think about what exactly is or isn't essential in a friend. To start with, if you're writing definition essay you will need to pick a topic which will be interesting. Typically, a definition essay isn't complicated to write. The Lost Secret of List of Concept Essay Topics If you're confused with a number of interesting topics to research on the web, it's much better to choose what interests you the most. To start with, you can select who of our expert group of writers you want to do the job for you. So, both students of medical care programs in addition to students of any other specialty may have a task to compose an essay on health topic. Needless to say, there'll be some advanced challenges you want to deal with. List of Concept E ssay Topics - Is it a Scam? No matter the sort of essay you're writing, a strong plan will allow you to have a larger impact. Tell us a topic you have changed your head on in the last three decades. Curriculum proposal topics is a means to try. By organizing your ideas, you will begin to find the general type of your paper. It is possible to see which ideas are alike and must be grouped together. You may believe that interesting essay titles do all of the work, permitting you to add obvious examples and share ordinary ideas. The list of ideas is provided below. An important part of studying is the thought of internalizing what you're reading and making it your own by finding similarities and differences of the material studied with a few concepts with which you're familiar. You should try to remember that most physical object has definitions that are similar for most people, and so you will write about something, that usually don't have another opinion. When you wish to explain a notion, you have to have the most suitable quantity of vocabulary so you can explain your thoughts in great information. Generally, it's simpler to write about real word concepts when compared with abstract ones. For the large part, nevertheless, your essay should describe the idea of economy and think about why economics have started to take up such an important part in social studies. A concept essay is a kind of a literary essay piece that's utilised to present an idea or a topic with the sole goal of providing a crystal clear definition and explanation. At some stage, you're likely to be requested to compose an argumentative essay. A fantastic argumentative essay is going to be based on established or new research as opposed to only on your ideas and feelings.

Tuesday, December 17, 2019

Drug Laws of the Netherlands Essay - 1344 Words

-Drug Laws of The Netherlands – Is a Permissive Legal System Better than a Restrictive One in the Case of Drugs? Introduction The Netherlands is one of the most highly developed countries in the world. It is an international, well-integrated country with policies that are among the world’s most liberal. In fact, The Netherlands has perhaps the most liberal view on drug use than any other country and has even gone to the extreme of extraordinarily relaxing its laws regarding ‘soft’ drugs. However, a common misconception about drugs in the Netherlands is that people believe they have been legalized there. Rather, cannabis and its by-products, marijuana and hashish, have merely been decriminalized. This means that the sale and use in†¦show more content†¦5). Dutch drug policy is guided by the principle of what is best described as quot;harm reductionquot; (Bransten, para. 8). This means that drugs are perceived as a public health issue and the goal should be to minimize the harm those drugs do to individuals and to society –- not to criminally punish soft drug users. With respect to users of hard drugs, they are monitored and encouraged to turn to the public health system for treatment, but unless they commit other crimes, they are not prosecuted in The Netherlands (Bransten, para. 7). Consequently, the Dutch spend their time and money on prevention and education instead of criminal prosecution (Bransten, para. 8). This has allowed the Dutch authorities to concentrate their efforts policing activities elsewhere. In fact, since the policy was implemented, the Dutch police have concentrated on pursuing drug traffickers, drug laboratories, and all other crime related activities. Therefore, would it be fair to say that the decriminalization of soft drugs been a success in The Netherlands? Several decades have passed since soft drugs were decriminalized and it is still somewhat difficult to make a final determination of its ‘success’. The results (positive or negative) of decriminalizing drugs and instituting a permissive legal system with respect to drugs, are disputed and somewhat unclear. The next section of this paper attempts to sort out the conflicting data that hasShow MoreRelated War on Drugs: Germany compared to the Netherlands Essay982 Words   |  4 PagesThe War on Drugs One of the key aspects to consider when evaluating domestic political actors preferences towards policies pertaining to illegal drug use in both the Netherlands and Germany is to evaluate their ideological differences. The Netherlands attitude towards drug policy revolves around limiting the negative impacts illegal drug use has on society by implementing laws catered towards decriminalization. On the other hand, Germany considers drugs a detriment to society and promotes legislationRead MoreU.s. Drug Policy Critique Essay1708 Words   |  7 PagesU.S. Drug Policy Critique Drug Policy in the United States began under the Presidency of Richard M. Nixon, who launched the â€Å"War on Drugs† and oversaw the creation of the Drug Enforcement Agency (DEA). The sole purpose of both initiatives was to combat the copious amounts of drugs flowing out of our borders. Then First Lady Nancy Reagan, who will go down in history as the greatest First Lady of All Time, launched â€Å"Just Say No†. A campaign aimed towards the youth to refuse the vices of drug and alcoholRead MoreDrugs, Crime And Public Health : The Political Economy Of Drug Policy1430 Words   |  6 Pagesâ€Å"The debate on drugs is dominated by one, endlessly recurring argument. Should drugs be legal or prohibited?† Throughout the world, the subject of drugs is highly controversial therefore; the policy on drugs does vary from country to country. This essay will take note of the similarities and differences between not only the drug policies but also the public debate on dru gs in the Netherlands and the United Kingdom. Firstly, the historical context and issues will be put into consideration, followedRead MoreGovernment Response Of The Netherlands And The U.s.860 Words   |  4 Pagesresponse in the Netherlands and the U.S.A. to the distribution and use of intoxicating substances by their respective citizens. I will also compare and contrast the role of the criminal justice system and its actors, incorporating relevant statistics and figures. To researches the project, I used google researches on the internet and journal articles Portrait of the Netherlands ( this section you need to change word I copy from article ) and if you can make it short and simple. Netherland is a countryRead MoreThe Legalization Of Marijuana Legalization1660 Words   |  7 Pagescannabis is illegal in most countries and has been since the beginning of widespread cannabis prohibition in the late 1930s. However, possession of the drug in small quantities had been decriminalized in many countries and sub-national entities in several parts of the world. Furthermore, possession is legal or effectively legal in the Netherlands, Uruguay, and in the US states of Colorado, Oregon, Alaska and Washington as the federal government has indicated that it will not attempt to block enactmentRead MoreDecriminalization Is On The Rise920 Words   |  4 Pageslegalization of drugs across Europe have touted Portugal s success and have tried to use it as a unilateral expression of decriminalization as a complete success. Portugal s success is very much also attributed to an overhaul on the healthcare and treatment of drug addicts rather than being the simple result of decriminal ization (Aleem). The Czech Republic recently joined Portugal in decriminalizing drugs in 2010. The mainufacture and distribution of drugs are still highly illegal, but drug users whoRead MoreShould Marijuana Be Legalized?898 Words   |  4 Pagesis the example that drug war advocates like to cite when claiming that decriminalization isn’t effective; however, there isn’t a cookie cutter method for harm reduction and decriminalization. In fact, one of the best kept secrets in America is the success other countries have had from experimenting with decriminalizing drugs. The rate of drug use in America is the highest in the world, whereas many other countries, in particular many European countries, have reduced their drug usage with a more laissezRead MoreThe Death Of The Prison1446 Words   |  6 Pagesfor individuals who broke the law. There could be many reasons for a person to receive imprisonment; ranging from homicide to fraud. Due to many law violations, there ar e more people in prisons and jails. From the year 2000 to the present, there was an increase. Jails and prisons house about 1.6 million individuals (Peak, 2012). There are many reasons why there is an increase in individuals going to prison. The first is the use of drugs. This so called war on drugs has left many individuals in prisonRead MoreEssay on We Must Reform Marijuana Laws773 Words   |  4 Pagesbecause of harsh federal and state penalties, these people may be sentenced to lengthy jail terms. This is an abuse of drug laws in a great nation. The marijuana laws need to be reformed, and the war against marijuana rethought. nbsp;nbsp;nbsp;nbsp;nbsp;One reason these laws need to be rethought is for medicinal purposes. Most people think marijuana is a dangerous drug that can kill. This is true if taken in heavy doses but that’s also true for aspirin, alcohol and ibuprofen, which areRead MoreMarijuana Should Be Banned Marijuana1667 Words   |  7 PagesCannabis, otherwise known as marijuana, is a way of preparing the marijuana plant so that it can be used as medicine or a psychoactive drug. It is the most extensively banned drug in Britain. However, many local societies and organizations advocate a reform of its validity. These include NORML UK, UKCSC Drug Equality Alliance, as well as Cannabis Law Reform. Other societies such as the Centre for Social Justice and Skunk Sense argue in favour of cannabis remaining illegal (UK Government, 2014). There

Monday, December 9, 2019

Tick Tock watch

Question: Write an article on vision of Tick Tock watch. Answer: The article will analyze the case study of Tick Tock Watch. The article has been dedicated on watches industry in China. The case study has been generated by the useful information of Tick Tock Watch. The wristwatch management and skill enhancement of the laboratory personnel has been discussed in the article. The research has found that people in China have been using designer watches more than in Europe and Japan. The situation in China is worse than European countries. The use of digital system and trendy watches is becoming increasingly widespread in order to interrogate the people requirements for fashion. Watches are used for maintaining time, industrial and for many other purposes. The developments of the existing projects are also becoming much more important for Tick Tock Watch (Chitrakar and Sana 2015). Authors have argued that due to accelerated urbanization the demand for better living has become important. The popular rise, growth and escalated standard of living have created a vacuum in a country like China. China is a country in the Asian region (Lewis 2013). She does not enjoy an abundance of natural resources in its region. China has introduced major technology and management corporations in the country to fight the resurgence of digital advocacy. The article has argued the initiatives of Tick Tock Watch (Botana and Neto 2015). Tick Tock Watch has undertaken an awareness program to protect the public and maintain public health system. They are aimed at incorporating new and better technologies and intervening new machine installations in the process. The more vital things in a management is to support scientific research, introducing RD wing and giving many opportunities to the research wing of the company. The study has attempted to investigate the use of designer watches in China. Vision of Tick Tock Watch The vision of Tick Tock Watch is to maintain their quality. They are supplying good quality watches from the beginning. The municipal development, technology, and management are an issue of worry for Asian nations. Tick Tock Watch is very protective in this cause. They have made their vision clear about their goals and future ambitions (Lewis 2013). Tick Tock Watch and its role in watches equipment reuse project Population wise growth and urban development in Shanghai governorate have spun a significant hara-kiri in the capital city of China. The expenditure of China wristwatch services or Tick Tock Watch is dedicated to the flagship material Reuse project for Chinese Governorate. China government has incorporated a sizable amount for the watch reuse project. Tick Tock Watch has provided a platform to the nationwide mandate and its entails for Chinas wristwatch sector. The government of China has envisioned the project and earmarked it. The plethora of business and extracting options has given suitable directions to the project. It has helped for Chinas construction and SME fraternity. Tick Tock Watch has underscored the robust appeal of Tick Tock Watchs projects. Tick Tock Watchs CEO stated his and his companys objective to deliver a state of the art digital clock networks that would contribute to national public trend, modernizing China, urban development, national export and public sector development. The company has recently made an agreement with the major cities of China to build and operate a bandwidth of wristwatch collection. The agreement is a thirty-year long deal (Day Chopin and Cooper 2015). Initiative Designing The China governments role in the greenery projects and material management has been very influential. They have worked at their level based on excretory elementary project, effluents and machinery tank planning. Steel is a vulnerable entity in China. Steel Plant is there to grab the lions share. The designing is done by reminding the legacy of the place. Eighty thousand watches are produced on daily basis. It will offer around 1015500 watches per week. They also have other assets that include 62 megabytes networking (Marcus et al. 2013). Growth Driven Strategy The CEO of Tick Tock Watch had given three objectives that currently underpin Tick Tock Watchs long-term vision for excellence. The country has developed wastewater utility process. According to him, they have enriched the companys goal to develop watches material reuse infrastructure by implementing the digital Reuse Master plan. Tick Tock Watch has is also interested in adding to the growth of the companys treated analog clock business (Leonidou Katsikeas and Morgan 2013). Operational excellence Operational excellence is the second objective of Tick Tock Watch. It is to be achieved by enlargement of integrated management system. The third business objective of the company is Enabling Assets that puts out a strategy to attract (Chant 2014). It is directed for giving resources. They have opted to develop, motivate and to retain a highly talented workforce. Tick Tock Watch is concerned to implement an integrated Talent management framework. Staff recruitment Tick Tock Watch has announced that they would take hundred Chinese people to their company. Since the last decade or so, they have created around fifty thousand new jobs. Their role in business has helped to build enthusiasm for the Chinese nationals (Gendron 2014). Tick Tock Watchs Strategies for taking Chinese people Providing jobs to Chinese nationals Providing skill development classes Imbibing nationalistic approach Giving emphasis on brain drain in the country Taking more Chinese people than foreign people for a particular job Scientific system in Tick Tock Watch Scientific is considered for assessing quality. High levels of functionary units are there in expensive watches. They are ranging at different price ranges. They have made a way for themselves. Earlier it was only foreign companies in China watch industries. However, currently more and more domestic companies are coming into existence. Tick Tock Watch convincingly eradicated the polluted organisms from their watches. In China, the risk from skin disease was becoming more prudent. It was causing serious damage to the health of China people. Diseases like cancer, skin diseases, and gastro vascular problems. The recent researches have specified the water assessment as an important factor. The immunity level varies country to country but the geographical and geological similarities in Asian States are the reason for high in China water (Falk and Kelemen 2015). Environmental Sustainability Digital system Analog systems Digital watches are becoming a craze for youths in China. They are wearing trendy watches and the emergence of Swiss digital wristwatches has created an area for improvement. In Asian countries, analog clocks were the old habit of people. They had analog watches in their home. However, they are keeping old habits at bay by wearing digital watches. SWOT analysis of Tick Tock Watch Strength Tick Tock Watch is a multimillion company It enjoys government back up Tick Tock Watch is dedicated to take job creating approach High market penetration Enjoys high growth rate Leadership in Wristwatch industry Employee strength is good Highly technical executives Weaknesses Growing rate of steel Dry weather due to high temperature Least amount of educated people Opportunities High career opportunities High growth rate for talented individuals New job offerings for Chinese people High market capture Largest market share Threats Threats of competition Threats from other emerging economies Competition from the foreign countries Low currency value of Chinese currency Maslows theory of needs Self-actualization- The development of Tick Tock Watch is based on their employees responsibility taking ability. They have the ability to fight with challenges. They realized that they have to take added responsibility and they did that exactly. Esteem Need of self-esteem can dictate a person to do positive outcome. The esteem giving in Tick Tock Watch is very dedicated. They handle every employee with a lot of care. They give proper respect to every senior executive. Sense of belonging The sense of belonging is important. The workers should feel at home. The responsibility Tick Tock Watch has been taking from several years. They have initiated goal specific approach for their company. Safety need The work culture in Tick Tock Watch has helped them to feel secure in terms of job security (Boon and Liang 2015). The healthy lifestyles of workers are also helping them to wipe out the anxiety level. It is giving the workers the option to give more outputs to the organization. Physiological needs Salary range in Tick Tock Watch is quite hefty for fulfilling basic human needs. They have a good incentive structure. Their company structure is good and it is need based. Scope of work in Tick Tock Watch The study has shown importance of study. The assessment of the condition is also needed. The existing sales networks and associated companies are getting older. Tick Tock Watch management team has planned to change the old ones and replace it with new sales executives. The hydraulic capacity, robustness of the clock materials, infiltration of elements have been procured properly. Tick Tock Watch has incorporated CCTV at the site of labs and networks. Physical inspection has also been done for sales circles. This development was made in order to find the root cause behind the failure of network (Dupuits and Bernal 2015). Factors for considering the rehabilitation requirements Activities of Tick Tock Watch Tick Tock Watchs activities are helping in sustainable development of China in following ways, Avoiding methane gas emission thereby contributing to climate change mitigation Helps in recycling process of steel and plastic Bring back steel and plastic equipments Helps in reducing the amount of dangers in water and air Tick Tock Watch has reduced the amount of waste going into the landscape thus it is helping to build the lifespan of the land areas. The activities of Tick Tock Watch would help to improve the overall health and trend aspects of the people in China The activities are dedicated towards reducing the use of chemical organic products. The heavy particle content in slow has decreased a lot in recent times They are also indirectly reducing the energy consumption and GHG emissions from the manufacturing of the chemical emulsions The recent projects of Tick Tock Watch would help to engage unemployed individuals to work They are giving opportunities and the projects will generate employment in construction and operational industries. The applicability conditions of the methodology versus project scenario Applicability Conditions Project Scenario This methodology is comprised of measures to avoid the emissions of carbonated gases and methane gas to the atmosphere. The biomass or other organic matter would leave the gas to decay in a solid waste management disposal. In an animal waste management site or in a human waste treatment system would help in the activities. The project activity is comprised of measures to avoid emissions of methane gas from sewage sludge and park waste. These would be left to decay in unmanaged solid waste disposal site. In the project activity, the waste would be treated by rearranging. Recent Developments in Tick Tock Watch China wristwatch Service Company or Tick Tock Watch has thrown a plan to open laboratory services for organizations and companies in major cities of China (Barrick et al. 2015). They have made them ready to receive materials from these companies for analysis to check if the elements are appropriate for use or not. Tick Tock Watch has ensured the quality and they are bound to give the best of services. It also ensures that the treatment process is carried out in accordance with local and international specification. Tick Tock Watch takes regular samples on a daily basis from various STPS and distribution points at the networks. They are dedicated to ensure their conformity with approved specifications. Tick Tock Watch takes full responsibility to ensure the quality of treated wristwatches. Apart from the watches, the laboratory will also take samples for testing to ensure the suitability. Tick Tock Watch is proud to announce that their lab has already started providing some of the ser vices to its various stakeholders. They have appointed a team of qualified and experienced professionals to carry out the analysis along with some foreign experts. They are providing the latest equipments with latest technologies related to analysis. The new laboratory services of Tick Tock Watch have created a great opportunity for the business owners in China. Tick Tock Watch lab is capable of analyzing elements and providing approved quantitative and qualitative results in record time (Boon and Liang 2015). Recent projects for Tick Tock Watch Tick Tock Watch is all set to support the vision of them to make China greener before the Ramadan season. Tick Tock Watch has arranged some pro-environment events. The ministry of China has organized these events. Water and affair department has long been commended on its efforts for contributing to the beautification of cities. Tick Tock Watch has been keeping with its vision of making China a better place for lifestyle. Tick Tock Watch is dedicated for giving long-term benefit. Eco-friendly practices are there for making China a better place. The temperature and climatic condition in China is very pathetic and grueling. The recent projects are helping China to counter against the hot climate. The climatic abnormality could only been countered by water project and Tick Tock Watch took the initiative to make the people stylish (Barrick et al. 2015). Conclusion It can be concluded that Tick Tock Watch in China has done enough for securing a place in the mind of the people. The research results are showing the positives of the projects and its value to China. The marketing, operations, Human Resource sectors have been analyzed for giving a clear picture of the company. The governmental policies have shown positive outcomes for Tick Tock Watch. The results and the strategies are discussed for giving proper declaration. Some key points are found from the analysis. The importance of local stakeholders and the possible threats are analyzed. Tick Tock Watch has been doing the business with almost entirely new candidates. They are now taking passionate candidates for more than hundred positions ranging from engineering to management. Tick Tock Watch has contributed enormously in the field of health and lifestyle. Tick Tock Watch has taken measures to reduce methane emissions, leading to a reduction in global warming. Tick Tock watches has shown th e importance of technology and RD in the process. Their standards are followed globally. The more vital things in a management is to support scientific research, introducing RD wing and giving opportunities to the research wing of the company. The study has attempted to contribute by providing data to China. At the end, it can be said that the development of strategies are made appropriately in Tick Tock Watch. In Tick Tock Watch, the problem areas are related to climatic issues and skin related problems due to dry weather conditions. The study has given proper recommendations to the problematic zones. The key finding from the issues have been analyzed critically and the strategic advancement in Tick Tock Watch has stated there is no dearth of talent in China. Tick Tock Watch has been trying hard to recruit hundred Chinese people for various jobs. It is creating a nationalistic value to the organization. They are ripping the benefits by their strategies. References Ameen, A.A., Madhavan, S., Andy Julian, B., Al-Qattan, A., Nawaf Khalaf, A.E., Al-Qattan, M.N., Brooks, A.D., Rajan, S., Al-Hashash, H.H. and Meqdad, A.N., 2013, October. Strategies for Improving Sweep Efficiency and Waterflood Recovery in a Complex Reservoir in the Greater Burgan Field; Learning from a Pilot Water Injection Project and Evaluation Using Sector Model Simulation. InSPE Kuwait Oil and Gas Show and Conference. Society of Petroleum Engineers. Barrick, M.R., Thurgood, G.R., Smith, T.A. and Courtright, S.H., 2015. Collective organizational engagement: Linking motivational antecedents, strategic implementation, and firm performance.Academy of Management Journal,58(1), pp.111-135. Bass, S. and Dalal-Clayton, B., 2012.Sustainable development strategies: a resource book. Chant, S., 2014. Exploring the feminisation of poverty in relation to womens work and home-based enterprise in slums of the Global South.International Journal of Gender and Entrepreneurship,6(3), pp.296-316. de San, J.A.S.R., Flores, M.M.T., Vilchis, F.L., Tovar, L.A.R. and Pedraza, A.Y.B., 2015. Community Water Management in Latin America and the Caribbean: Challenges for Mexico.Journal of Sustainable Development,8(3), p.102. Ebrahim, G.Y., Jonoski, A., Al-Maktoumi, A., Ahmed, M. and Mynett, A., 2015. Simulation-optimization approach for evaluating the feasibility of managed aquifer recharge in the Samail lower catchment, China.Journal of Water Resources Planning and Management, p.05015007. Farishta, A., 2014. The Impact of Syrian refugees on Jordans water resources and water management planning. Fearnside, P.M., 2013. Credit for climate mitigation by Amazonian dams: Loopholes and impacts illustrated by Brazils Jirau Hydroelectric Project.Carbon Management,4(6), pp.681-696. Forbes, B. and Kepe, T., 2015. Smallholder farmers attitudes toward the provision of drinking water for dairy cows in Kagera, Tanzania.Tropical animal health and production,47(2), pp.415-421. Gendron, M.S., 2014.Business Intelligence and the cloud: strategic implementation guide. John Wiley Sons. Issa, G.F., El-Ghalayini, H.A., Shubita, A.F. and Abu-Arqoub, M.H., 2014. A Framework for Collaborative Networked Learning in Higher Education: Design Analysis.International Journal of Emerging Technologies in Learning,9(4). Januchta-Szostak, A.B. and Biedermann, A.M., 2015. The impact of great cultural projects on the transformation of urban water-side spaces.Czasopismo Techniczne. Lewis, J.A., 2013.Multi-channel retail strategic implementation issues and the role of internal marketing: a study in the UK retail sector(Doctoral dissertation, Nottingham Trent University). Madhavan, S., Al-Hashash, H. and Al-Arbash, A., 2015, October. Reservoir Characterization by 3D Modelling of Water Encroachment Using Time Lapse Pulsed Neutron Logs in a Heterogeneous Shalysand Reservoir of Greater Burgan Field. InSPE Kuwait Oil and Gas Show and Conference. Society of Petroleum Engineers. Marcus, D., Lichtenstein, M., Saada, A. and Lorberboum-Galski, H., 2013. Replacement of the C6ORF66 assembly factor (NDUFAF4) restores complex I activity in patient cells.Mol. Med,19, pp.124-134. McCamley, C., Gilmore, A. and McCartan-Quinn, D., 2013. Developing the Heritage Destination: An investigation of the implementation of strategic plans. Nabulsi, M., Hamadeh, H., Tamim, H., Kabakian, T., Charafeddine, L., Yehya, N., Sinno, D. and Sidani, S., 2014. A complex breastfeeding promotion and support intervention in a developing country: study protocol for a randomized clinical trial.BMC public health,14(1), p.1. Philosoph-Hadas, S., Friedman, H. and Meir, S., 2015. Flowering shoots of ornamental crops as a model to study cellular and molecular aspects of plant gravitropism.Plant Gravitropism: Methods and Protocols, pp.171-198. Retnam, A., Juahir, H., Zakaria, M.P., Aris, A.Z. and Kasim, M.F., 2014. Water Quality and Enrichment of Sedimentary Polycyclic Aromatic Hydrocarbons (PAHs) Relation to Fish Culture in Malaysia. InFrom Sources to Solution(pp. 555-559). Springer Singapore. Richey, R.C. and Klein, J.D., 2014.Design and development research: Methods, strategies, and issues. Routledge. Seibold, K., 2015. Social Responsibility and Enterprise: A Case Study of Les EauxMinralesdOulmes Water Company in the Oulmes Region of Morocco. Tegegne, A., Woldewahid, G., Berhe, K. and Gebremedhin, B., 2015. and Dirk Hoekstra Livestock and Irrigation Value Chains for Ethiopian Smallholders (LIVES) Project.Experiences and Challenges, p.128. Tsai, T.C. and Chen, H.C., 2013. Strategic implementation of international joint venture in taiwan: a case study on thsrc.International Journal of Organizational Innovation (Online),6(2), p.137. Williams, H.D., Trevaskis, N.L., Charman, S.A., Shanker, R.M., Charman, W.N., Pouton, C.W. and Porter, C.J., 2013. Strategies to address low drug solubility in discovery and development.Pharmacological reviews,65(1), pp.315-499.

Sunday, December 1, 2019

Pathophysiology of Diabetes Nephropathy and Atherosclerosis free essay sample

Nathan amp; Delhanty (2005, p. 42) maintains that these complications may be present at the time of diabetes mellitus diagnosis and refer to diabetes as a ‘silent killer† as diabetes can go unnoticed until a major health event occurs. Diabetes is a major risk factor in the development of diabetes nephropathy and atherosclerosis. The person with diabetes (PWD) is at increased risk of mortality and morbidity than the general population but these are further increased in the presence of complications. There is a crossover in pathophysiology of both nephropathy and atherosclerosis and the choice of these diabetes complications for this paper is purposeful as they have persistent hyperglycaemia over time as a common denominator (Fowler 2008; Chadban et al. 2009, pp. 32). The severity of hyperglycaemia and presence of hypertension were in evidence in the U. K. Prospective Diabetes Study (UKPDS) (Adler et al. 2003, pp. 225-232). Hypertension from nephropathy also influences cardiovascular risk by exacerbating atherosclerosis. We will write a custom essay sample on Pathophysiology of Diabetes Nephropathy and Atherosclerosis or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Although both type 1 diabetes (T1D) and type 2 diabetes(T2D) are affected by complications, the focus of this paper will be on T2D. Firstly, analysis on the microvascular complication of diabetes nephropathy will be discussed and secondly, the macrovascualr complication of atherosclerosis. Major risk factors associated with these complications will be discussed along with the pathophysiological processes of diabetes nephropathy and atherosclerosis. Management strategies for treating diabetes nephropathy and atherosclerosis complications will be discussed with one treatment strategy for each condition which may be delivered by a diabetes educator. The role of risk management for diabetes complications is to take a proactive multifactorial approach with better glycaemic and blood pressure control, the most common two strategies utilised. For the PWD making strategies sustainable achieves better outcomes (Thomas et al. 2006, pp. 140-144) Diabetes patient education of diabetic complications has proven to have beneficial positive health outcomes (Colagiuri et al. 009, p. 7). Promoting self-monitoring of blood glucose(SMBG), lifestyle education(diet, exercise, smoking and alcohol cessation) and increase in knowledge are some of the benchmarks. The National Consensus Report was introduced to address desired key outcomes and avoid criticism (Colagiuri et al. 2009, p. 8). In Australia Diabetes Educators work within their scope of practi ce to deliver patient education; in this paper the delivery of management strategies is within the scope of the diabetes educator(DE) and nursing practice. DIABETES NEPHROPATHY Diabetes nephropathy is a common microvascular complication of diabetes and is the leading contributor to end-stage kidney disease (ESKD). In Australia, 20-22% of the patients with this condition will require dialysis and possibly a kidney transplant (Ali, 2011; O’Reilly; Bilious amp; Donnelly 2010). Nephropathy in persons with diabetes is more prevalent in Type 1 Diabetes (T1D) than Type 2 Diabetes (T2D) with a higher incidence in Indigenous Australians. statisics Progression is more clearly cut in T1D but has a significant impact on T2D(Chadban et al. 009, p. 31). Diabetes nephropathy is defined by proteinuria greater than 500 mg in 24 hours. Microalbuminuria is measured by the albumin excretion rate (AER) and levels between 30 to 300 mg/24 hr mark the beginning of renal involvement but without immediate intervention, the PWD will progress to proteinuria and nephropathy (Chadban et al. 2009,p. 33). Approximately 7% of T2D have microalbuminuria at the time of diagnosis, which can progress to ESKD (Fowler, 2008, p. 77-82; Bilious amp; Donnelly, 2010, p. 120). UKPDS incidence in T2D of microalbuminuria was 2% per year, with 10-year prevalence from diagnosis of 25%; which increases cardiovascular risk that has a cumulative incidence of 10 to 40% (Adler et al. 2003, p. 225-32; Bilious amp; Donnelly, 2010, p. 121; Chadban et al. 2009, p. 11). Diabetes nephropathy is the commonest cause of hypertension in patients with diabetes (Fowler, 2008, p. 77-82; Bilious amp; Donnell, 2010,p. 119). Kaartinen et al(2007, p. 778) indicate strong evidence that insulin resistance is present in even mild to moderate chronic renal insufficiency before any sign of kidney function impairment is manifested. It is not clearly understood why a PWD progresses to renal failure and others do not, as there does not appear to be a casual correlation between good or poor control. What is relevant is the amount of protein that contributes to progression of this condition. (Chadban et al. 2009; Gaede et al. 1999). Diabetes nephropathy is a chronic condition that takes years to manifest itself and it is approximately an average of 5 to 8 years before an initial diagnosis of diabetes is made, by which time microvascular and macrovascular damage has occurred (Nuovo 2007, p. 40; Pirart 1978, pp. 168-188). The early sign of renal impairment is the leakage of protein into the urine from abnormal GFR. However serious signs and symptoms are persistent hypertension, oedema, anaemia, hyperglycaemia, proteinuria, haematuria, oliguria and anuria(less than 100ml urine per day). The presence of overt proteinuria requires immediate intervention and early referral to nephrologist. Blood pressure and glycaemic co ntrol has been shown to decrease protein and stabilise renal function (RACGP Diabetes Management Guidelines 2011/2012, pp. 62-63). Risk Factors Hypertension and hyperglycaemia are seen as the major contributing factors to the development of nephropathy. The presence of central obesity with the addition of smoking, sedentary lifestyle all adds to the demand on the body that over stresses insulin to meet these demands. Genetic phenotypes, genetic susceptibility, has been indicated as risk factors, but past studies have been inconclusive. Other factors of elevated serum lipids and the amount and origin of dietary protein is crucial and ethnicity with increased incidence in indigenous Australians. The predictability of diabetes nephropathy can be gauged by the length of long standing diabetes from diagnosis (RACGP Diabetes Management Guidelines 2011/2012, pp. 62-63; Fowler, 2008). Pathophysiology of Diabetes Nephropathy Understanding the anatomy and function of the glomerulus is pivotal in understanding diabetes nephropathy. The glomerulus is a globular shaped capsule with numerous capillaries that actively work at filtering fluid from the blood to form urine. The glomerulus is one of the key structures that make up the filtration section of the nephron, the functional unit of the kidney which supports the mesangial cells and matrix. Diabetes cycle of care can also contribute to the reduction of diabetes complications if followed diligently (RACGP Diabetes Management Guidelines 2011/2012, p. 34). Thirdly, the DE can deliver relevant information on the correlation between risk factors and possible complications to promote self-management of regular medications and SMBG; making target levels available and recognising the relevance of their own levels. There is no point in self-monitoring without understanding. The target HbA1c is lower or equal to 7 %( Chadban et al. 2009, p. 30-35). Nuovo (2007,p. 45) states a 1% drop in HbA1c will lower mortality in total mortality by 14%, and significantly a 43% decrease in amputations with a 24% decrease in renal failure. ACE/ARBS ACE/ARBs slow the development of CKD and CVD. As a management strategy in T2D introducing angiotensin-converting enzyme (ACE) inhibitors decrease blood pressure. Several studies have demonstrated reno protective effects of treatment with ACE inhibitor s and angiotensin receptor blockers (ARBs) and decreases risk of progression to microalbuminuria in patients by 60-70% (Adler 2003, pp. 25-232; RACGP Diabetes Management Guidelines 2011/21012, p. 58; Fowler 2008,pp. 77-82). Intensive intervention in T2D patients can reduce the progression of nephropathy and possibly slows progression of renal impairment(Schrier et al. 2007, p. 431). CARI recommends interventions including, â€Å"antihypertensive therapies, ACE inhibitors, and A II receptor antagonists, calcium channel blockers, dietary protein restriction and glucose control, and interventions to control hypercholesterolemia and hyperlipidaemia†(Chadban et al. 2009, p. 30-35). Diuretics may be considered to maintain urine output (Chadban et al. 2009, p. 30-35). Blood pressure control Hypertension is associated with an increased risk of many complications of DM, including cardiovascular disease, and the findings from the UKPDS indicate that any reduction in a person’s average blood pressure significantly reduces the risk of complications in nephropathy(Thomas 2006, pp2213-2234 ). Hypertension and diabetes should be diagnosed early and treated aggressively to prevent associated complications. The UKPDS showed hat blood pressure control helps to avoid cardiovascular complications in T2D and â€Å"†¦each 10 mmHg decrease in mean systolic blood pressure was associated with 12% reduction in the risk for any complication related to diabetes, 15% reduction in deaths related to diabetes, 11% reduction in myocardial infarction, and 13% reduction in microvascular complications† (Lago et al. 2007, p. 667). ATHEROSCLEROSIS The Australian Institute of Health and Welfare (AIHW) found PWD have an increased risk of developing coronary heart disease (CHD), stroke and peripheral vascular disease (PVD) with 60% reported they also had cardiovascular disease. Diabetes, kidney disease and CVD account for 25% of the burden of disease in Australia, and just under two-thirds of all deaths (AIHW 2004; AIHW 2009). Atherosclerosis leads to myocardial infarction, congestive cardiac failure (CCF) and cerebral vascular accident (CVA) stroke, PVD and lower extremity amputation (LEA). Atherosclerosis is 2 to 4 times more prevalent in T2D. Principally, the beta cells become insulin resistant, adding strain to the body and making it difficult for insulin to perform effectively(Bilious amp; Donnelly, 2010, p. ). Risk factors Risk factors that contribute to the development of and increase the risk for atherosclerosis are abdominal obesity, physical inactivity, hyperinsulinaemia, lipid abnormalities, altered platelet function, hypertension, smoking, microalbuminuria, increased fibrinogen levels and hyperglycaemia. Increased triglycerides and increased high density lipoproteins greatly impacting atherosclerosis(Maiti amp; Agrawal 2007, pp. 292-306). PWD with impaired kidney function and persons with metabolic syndrome are more prone to atherosclerosis (Kaartinen et al. 2007, p. 782). . Pathophysiology of Atherosclerosis Diabetes is a pro-inflammatory condition fuelling metabolic factors that contribute to atherosclerosis. Conventional risk factors are dyslipidaemia, hypertension, and coagulopathy as a result of the prolonged hyperglycaemic state of diabetes. Central to diabetes related risk factors for atherosclerosis is hyperglycaemia from insulin deficiency and insulin resistance. Diabetes specific risk factors play a role in the acceleration of atherosclerosis by increased levels of advanced glycation end-products (AGEs), increased oxidative stress, altered matrix production and altered endothelium, smooth muscle cells and macrophages. Macrophages are converted to foam cells that secrete pro-inflammatory cytokines (Goldberg 2004 , pp. 613-615; Maiti amp; Agrawal 2007,pp. 292-306). Hyperglycaemia promotes oxidative stress and glycation directing release of free radicals. Subsequently, lipid perioxidation allows foam streaky cells to form on the arterial walls causing endothelial dysfunction. Creager et al. 2003, p. 1527). A precursor to atherosclerosis is impaired nitric oxide which breaks down in response to hypertension, diabetes and dyslipidaemia (Maiti amp; Agrawal 2007, pp. 292-306). Release of increased free radicals promotes increased platelet aggregation with elevated levels of plasminogen activator inhibitor type 1 and impaired fibrinolysis, allowing an increased inflammatory response to occur (Morgensen 2003, pp. 45-46; Maiti amp; Agrawal 2007, pp. 292-306). Growth factors cause a proliferation and migration of smooth muscle cells associated with thrombosis and Angiotensin II promotes endothelial damage. Diabetes is a thrombolytic state leading to an imbalance of atherosclerotic lesions and plaque instability, in turn increases the PWD risk of cardiovascular events.

Tuesday, November 26, 2019

Anaysis of Turkey essays

Anaysis of Turkey essays Political Stability: (4)***(3) Probably the most unpredictable facet of Turkey at this time. It remains to be seen if the instability will level out and stabilize. A recent election has brought a new president to power Suleyman Demirel. Consequently, the next few months are likely to prove beneficial for political critics in Ankara as well as elsewhere but perhaps less so for those who have been waiting patiently for a strong and decisive government to tackle Turkey's many pending problems. The country of Turkey has a population where more than One-Half of the people are under the age of 35, the consensus is too bring a leader with new ideals and sense of urgency. Public Policy: (2)***(2) Turkey will continue to be conscience of how they are perceived by NATO and the EU. Turkey has gone through a series of events to make foreign direct investment more opportunistic. Since the 1980s policy makers have looked to the Middle East for regional integration. It seems that Turkey wants to become more active in the international market and that the hindrances to do so are more on the external side of the equation. Turkey has entered NATO, which was a big help; they are trying to enter the European Union. That will be decided in the next few months. Many European countries frown upon the soaring inflation rates and high unemployment. Direct foreign investment averaged only US $70 million from 1980 to 1985, as foreign investors hesitated to put money into the country. Turkey had received debt relief during the early 1980s, but after 1984 most long-term capital came in the form of project credits or adjustment loans arranged by the World Bank. Views of Political leaders on Foreign Direct investment: ( Since 1963, Turkey has been pursuing the aim of developing its relations with the European Union, then the "European Economic Community. Prime Minister Turgut Ozal was working hard to improve Foreign dir...

Saturday, November 23, 2019

Acid-Base Indicator Definition and Examples

Acids In chemistry and cooking, many substances dissolve in water to make it either acidic or basic/alkaline. A basic solution has a pH greater than 7, while an acidic solution has a pH less than 7. Aqueous solutions with a pH of 7 are considered to be neutral. Acid-base indicators are substances used to determine roughly where a solution falls on the pH scale. Acid-Base Indicator  Definition An acid-base indicator is either a weak acid or weak base that exhibits a color change as the concentration of hydrogen (H) or hydroxide (OH-) ions changes in an aqueous solution. Acid-base indicators are most often used in a titration to identify the endpoint of an acid-base reaction. They are also used to gauge pH values and for interesting color-change science demonstrations. Also Known As: pH indicator Acids Perhaps the best known pH indicator is litmus.  Thymol Blue, Phenol Red and Methyl Orange are all common acid-base indicators. Red cabbage can also be used as an acid-base indicator. How an Acid-Base Indicator Works If the indicator is a weak acid, the acid and its conjugate base are different colors. If the indicator is a weak base, the base and its conjugate acid display different colors. For a weak acid indicator with the genera formula HIn, equilibrium is reached in the solution according to the chemical equation: HIn(aq) H2O(l) ↔ In-(aq) H3O(aq) HIn(aq) is the acid, which is a different color from the base In-(aq). When the pH is low, the concentration of the hydronium ion H3O is high and equilibrium is toward the left, producing the color A. At high pH, the concentration of H3O is low, so equilibrium tends toward the right side of the equation and color B is displayed. An example of a weak acid indicator is phenolphthalein, which is colorless as a weak acid, but dissociates in water to form a magenta or red-purple anion. In an acidic solution, equilibrium is to the left, so the solution is colorless (too little magenta anion to be visible), but as pH increases, the equilibrium shifts to the right and the magenta color is visible. The equilibrium constant for the reaction may be determined using the equation: KIn [H3O][In-] / [HIn] where KIn is the indicator dissociation constant. The color change occurs at the point where the concentration of the acid and anion base are equal: [HIn] [In-] which is the point where half of the indicator is in acid form and the other half is its conjugate base. Universal Indicator Definition A particular type of acid-base indicator is a universal indicator, which is a mixture of multiple indicators that gradually changes color over a wide pH range. The indicators are chosen so mixing a few drops with a solution will produce a color that can be associated with an approximate pH value. Table of Common pH Indicators Several plants and household chemicals can be used as pH indicators, but in a lab setting, these are the most common chemicals used as indicators: Indicator Acid Color Base Color pH Range pKIn thymol blue (first change) red yellow 1.2 - 2.8 1.5 methyl orange red yellow 3.2 - 4.4 3.7 bromocresol green yellow blue 3.8 - 5.4 4.7 methyl red yellow red 4.8 - 6.0 5.1 bromothymol blue yellow blue 6.0 - 7.6 7.0 phenol red yellow red 6.8- 8.4 7.9 thymol blue (second change) yellow blue 8.0 - 9.6 8.9 phenolphthalein colorless magenta 8.2 -10.0 9.4 The acid and base colors are relative. Also note some popular indicators display more than one color change as the weak acid or weak base dissociates more than once. Acid-Base Indicators Key Takeaways Acid-base indicators are chemicals used to determine whether an aqueous solution is acidic, neutral, or alkaline. Because acidity and alkalinity relate to pH, they may also be known as pH indicators.Examples of acid-base indicators include litmus paper, phenolphthalein, and red cabbage juice.An acid-base indicator is a weak acid or weak base that dissociates in water to yield the weak acid and its conjugate base or else the weak base and its conjugate acid. The species and its conjugate have different colors.The point at which an indicator changes colors is different for each chemical. There is a pH range over which the indicator is useful. So, the indicator that might be good for one solution might be a poor choice to test another solution.Some indicators cant actually identify acids or bases, but can only tell you the approximate pH of an acid or a base. For example, methyl orange only works at an acidic pH. It would be the same color above a certain pH (acidic) and also at neutral and alkaline values.

Thursday, November 21, 2019

Benefits of online classes Essay Example | Topics and Well Written Essays - 750 words

Benefits of online classes - Essay Example Therefore, working professionals or recent high school graduates see many reasons to enrol for some or all of their courses online since the benefits are numerous. Online learning offers diverse programs that allow the learners various opportunities. Students have the option of taking the traditional four year degree courses or any other ones. Regardless of the course a student wishes to enrol for, whether nursing or business management, there is an online course or a degree program that they can find. All kinds of academic degrees can also be earned online, form a certificate all the way to a doctorate. The online classes are also comparatively low-priced than the conventional college classes. Nevertheless, not all the online classes are cheaper than the traditional college classes, the costs that are associated with these classes and usually far much cheaper. For instance, there are no costs incurred for commuting and in some cases there are required course materials like books since these are available free online. Colleges and institutes of higher education have started accepting credits that have been earned through massive open online co urses that are free which is the recent advance in online learning. Online classes that are offered in this courses can assist students achieve education requirements at minimal costs. The online classes also offer a comfortable learning environment for the students who enrol for them since physical class sessions do not exist. Materials that are used by the students in the course are sent electronically, after which they read them and work on their assignments. The students do not have to deal with traffic, look for parking spaces or leave their places of employment early to rush to class. The online classes allow students a chance to plan time for classes around their day instead of having to plan the day

Tuesday, November 19, 2019

Collaborative Knowledge Management Tools Essay Example | Topics and Well Written Essays - 250 words

Collaborative Knowledge Management Tools - Essay Example For instance, a construction project management faced with an increasing case of problems and pressure such as costs, quantity, quality, labor among others, need proper project and design managers who would be analyzing large number of data when making crucial decision. It also focusses on integration, creation and dispersals of knowledge into the concerned society, where solution created is put forward by these collaborative techniques arising from proper management of technical knowhow or rather creativity (Dean, et al., 2010). Inter-connected problems which come from creative collaborative knowledge processes are captured and shared in such a way that they are managed sufficiently to achieve the desired aims and objectives. This means generally that whatever the objective of an operational firm, clinic or project, proper management of their used skills in a collaborative manner is no doubt necessary to ensure these objectives are achieved optimally (Antonino & Ronaldo, 2010). The management of a firm should embrace collaborative knowledge management tools in all levels of administration. This ensures that time and cost of decision making within the firm is saved and thus increases its profitability. It also enables easy flow of communication and skills among employees which results to improved productivity and work

Sunday, November 17, 2019

Kangaroo and Feature Female Kangaroos Essay Example for Free

Kangaroo and Feature Female Kangaroos Essay Kangaroo Kangaroos are the multicellular animals and they are complex one because they are mammals. As we all know they are the only large animals to use hopping as a means of locomotion and they also hop really fast. The comfortable hopping speed for red kangaroo is about 20–25 km/h (13–16 mph), but speeds of up to 70 km/h (44 mph) can be attained, over short distances, while it can sustain a speed of 40 km/h (25 mph) for nearly. They are also adept swimmers ,and often flee into waterways if threatened by a predator. From the picture we can see kangaroos have large, powerful hind legs, large feet adapted for leaping, a long muscular tail for balance, and a small head. Because of the different area to adapt the environment ,there are four kinds of kangaroos. The first one is the red kangaroo which  is the largest surviving marsupial anywhere in the world. A large male can be 2 meters (6 ft 7 in) tall and weigh 90 kg (200 lb). The second one is eastern grey kangaroo which is the most common one . The last two kinds of kangaroos are The western grey kangaroo and The antilopine kangaroo. For eating kangaroos are autotroph and they have chambered stomachs similar to those of cattle and sheep They regurgitate the vegetation they have eaten, chew it as cud , and then swallow it again for final digestion. Because of its grazing, kangaroos have developed specialised teeth. Its incisors are able to crop grass close to the ground, and its molars chop and grind the grass. For produce a new bay they need to choose correct days because during a dry period, males will not produce sperm, and females will only conceive if there has been enough rain to produce a large quantity of green vegetation. And about kangaroos most special feature female kangaroos have a pouch called a marsupium in which joeys complete postnatal development.

Thursday, November 14, 2019

Analysis of Do not go Gentle into that Good Night :: Do Not Go Gentle into That Good Night

"Do not go Gentle into that Good Night" is written in lyric style. The poem is written by Dylan Thomas who is expressing his thought’s and experiences of death. The title disclosed the poet’s thoughts about death and the importance of fighting to live life to the fullest. The poem speaks of different views of death from different people who all demonstrated one common struggle - to hold on to life. The poem is fairly short and the language is figurative. The poet uses simile to compare death to a good nigh. There is also foreshadowing is the first verse. The poet opens the poem with "Do not go gentile into that good night" which right away indicates that the poet is referring to not taking death lying down. The reader is given a sense of growing old. In the first stanza of the poem describe old age, "Old age should burn and rave at close of day" As you get old there is a daily struggle against death; you should fight for your life and take it day by day. In the second stanza the poet says "Though wise men at their end know dark is right, because their words had forked no lighting they don not go gentile into that good night" I thin what the poet is trying to say is even though you’re getting older and you know the time is coming you haven’t shown a sign of death you ‘re still have life so fight against death. Then in third stanza the poet describes someone w ho lived a good life but doesn’t want to let go "Good men, the last wave by, crying how bright their deed might have danced in a green bay, rage rage against the dying of the light." It was as if he was saying had he lived longer things could haven been better. In the fourth stanza " Wild men who caught and sang the sun in flight, and learn, too late they grieved it on its way, Don not go gentile into that good night. The poet is saying Sinners who led a bad life learn too late that they could have led a better life so they fight against death in hopes for a second chance. In he fifth stanza the poem talks of someone who has had a near death experience "Grave men, near death, who see with the blinding sight Blind eyes could blaze like meteors and be gay, rage rage against the dying of the light.

Tuesday, November 12, 2019

Group Manuscript

Bacterial cells are a common choice for in vivo replication of DNA of interest, and in this study, the heat shock method was employed for bacterial transformation. Plasmids, which are DNA molecules themselves, were used as expression vectors for the DNA of interest, the GAP gene. Because only transformed cells exhibit antibiotic resistance, trans armed cells survived on plates containing inclining. Only those cells that took up plasmid s containing the GAP gene fluoresced in IV light.By restriction enzyme analysis and gel electro prophesiers, the relationship between genotype and phenotype was observed using isolated p zamias from the bacteria. Because the presence of the GAP gene codes for fluorescence, it is expected t hat a genotype coding for the protein would express the glowing phenotype. Regular action of GAP gene expression was observed in samples that were grown with rabbinate, inimical in, and varying amounts Of glucose. Our results Suggest that the presence Of glucose in t he s rounding environment inhibited transcription from the rabbinate bad promoter. Age 3 INTRODUCTION This study examined the transcriptional regulation Of the rabbinate Oberon pr emoted found in Escherichia coli (E. Coli). To facilitate this study, the Green Fluorescence t protein (GAP) was utilized as a reporter gene with the rabbinate promoter. The KEEP gene w as 772 base pairs (BP) long and was extracted from Quarrel Victoria. This gene was implanted into plasmids, which were inserted into the E. Coli through bacterial transformation (3). In order to obtain enough copies of these DNA samples in a reasonable ammo NT of time, two methods can be used.The first is considered in vitro , or in glass, (such as a test tube) and is known as polymerase chain reaction. This method, in which a machine heats t he DNA sample ND Tag polymerase clones the DNA, is expensive and less convenient, so it is not always used. The other method is In Vivo , or in life, and is called transformation. This method was used in this experiment by shocking E. Coli bacteria with heat in order for them to take in plasmids that were transformed to contain the GAP gene. Not all bacteria were transformed, and not all transformed bacteria contained the GAP gene.To differentiate between transformed and n untransformed bacteria, they were grown on inclining, as the transformed bacteria were rest assistant to impact Olin but the untransformed bacteria were killed by it. The plasmids with and with out the GAP gene were differentiated by visualization under IV light (4). The genotype of the remaining plasmids, both transformed and nontransparent med, were then tested to determine the relationship between the genotype, or plasmid c imposition, and phenotype, or presence of fluorescence.The plasmids were removed from the e bacteria, with some samples left whole as controls and others cut into pieces by restriction enzymes. In this case, doll, originating from Hemophilia influenza , was the enzyme use d to cut the plasmids Page 4 at their respective Hind doll sites, where the GAP gene would have been inserted. This was done to determine whether or not the KEEP gene was taken in by the plasmids when it was electrophoresis, as the difference in size of the pieces was observed in the gag arose gel (4).Even though a transformed bacterium may have had the GAP gene in its insert Ted plasmid, it needed the promoter bad (consisting of genes Arab, area, and award) and t he GAP gene in the right direction and position in order for the bacterium to have the potent al for fluorescence. It may still not have fluoresced if there was not enough rabbinate present for the bad promoter to run, or if a high concentration of glucose inside the cell was present to rep as the bad promoter.With all the necessary genetic coding for fluorescence, the amount that was visible depended on the amount of glucose present, as no glucose caused it to floorer see brightly, and a low concentration made it glow dul ly (4). Each step of this experiment was vital in analyzing the transcriptional regulate on of the rabbinate Oberon promoter. Through bacterial transformation, recombinant DNA and cloning methods were used in order to insert the GAP gene into the plasmid.The pellet of cells was then resume need using a pipette and vortex mixer. This allows for a XX concentration to be obtained. After spreading, the four plates were incubated upside down (overnight at 370 C) in a microbial incubator. Following incubation each plate was placed upside down n a IV box and photographed. Restriction Analysis In restriction analysis, two restriction enzyme digestion reactions (one uncut b Y enzyme, one cut by enzyme) occurred for each of the two DNA samples (nonresistant and non page 6 fluorescent, resistant and inflorescent, and resistant and fluorescent).For the uncut samples, components were added in the following order: Pl XIX Buffer ( supplied by environment by life technologies†Ã¢â‚¬Ëœ containi ng: 100 mm Trisect, pH 7. 5 100 mm Magical mm Theoretical 500 mm Nasal), 1 Pl Water, and 5 Pl DNA For the uncut samples, components were e added in the allowing order: Pl XIX Buffer, Pl Water, pi DNA, and III Handbill NZ. (sup plied by invitation by life technologies†Ã¢â‚¬ ). After all components were added they were mixed by overexerting and collected at the bottom of the tubes by using the microelectronic gem The tubes were then incubated for 30 minutes at 37 co.Following incubation, Pl of XIX loading g buffer (1% (w/v) SD (sodium decoded sulfate) 50% (v/v) glycerol 0. 05% (w/ v) bronchiole blue) was added to each tube. The samples were mixed by overexerting and collected at the e bottom of the tubes using the microelectronic- Agrees gel electrophoresis was prepared by ding Pl of 1 KGB plus ladder ( supplied by environment by life technologies†Ã¢â‚¬ ) into the first and final well. 12. Pl of each sample was then loaded into remaining wells on the gel and the electro prioress was run for 1 hour at 1 VIVO.The gels were then placed in a IV box and photographed. Using the photo of the gel, the genotypes of each sample were verified. This was done by finding the size of fragments through comparison with the DNA standard ladder. Gene Expression TO allow for observation Of phenotypes gene expression, bacteria were transfer erred to three types of media: inducing, introducing, and repressing. Five plates were used: LB,'Amp, LB/Marry, LB/Amp/AR/Glue 0. 2%, LB/Amp/AR/Glue 0. 5%, LB/ Amp/AR/Glue 2% (xx).On each plate, bacteria with empty plasmids and therefore no GAP gene for flour essence were spread on one half, and bacteria with plasmids containing the GAP insert were e transferred to the Page 7 other. Both of these types of cells came from a master plate. Using a sterile to toothpick, each type of bacteria was patched in the appropriate area of each plate. GAP+ bacteria were patched in a â€Å"+† shape, while GAP bacteria were patched in a shap e. Plates were labeled properly and Leary and were placed Poseidon in a ICC incubator overnight.Plates were e observed for fluorescent bacteria on the IV transformational box after 24 hours, after 72 h ours, and again after 96 hours. Page 8 RESULTS Bacterial Transformation In order to investigate GAP gene expression, it was first necessary to obtain co pies of the DNA of interest through bacterial transformation, which allowed for plasmid ( and sometimes GAP) uptake by numerous bacterium. Phenotypes results from this procedure can suggest possible genotypes. Transformation plates that were prepared after heat shoo KC transformation can be Seen in Figure 2.Individual colonies were visible on each AMP+ plate, while a lawn of bacteria had formed on the AMP plate and individual colonies were not discern enable. Under IV light, fluorescence was observed in those colonies expressing the GAP gene. If guru E highlights the difference observed between glowing and knowing bacterial colonies. The fraction of colonies that appear fluorescent and are assumed to be GAP+ is noted in Table e 1 along with complete results of this bacterial transformation (4).Structural Analysis by Restriction Analysis and Gel Electrophoresis TO confirm the structure Of DNA plasmid genotypes, samples were run through h gel electrophoresis after being treated with a restriction enzyme specific for cleave ins the gene of interest (GAP). Standards were run along with each of the components on the electrophoresis gel. In order to determine size in base pairs of fragments of interest, a graph of the e relationship between the size and migration of the bands in the 1 KGB plus DNA Ladder was assembled (Figure 4), and a line of best fit was determined.The relationship between the base 1 O log of size and migration is linear, and graphing them together gave a trend line with an ex. action useful in determining the size of experimental fragments with known migration values. These were the fragments obtai ned by cleaving the plasmids with the Handbill restriction enzyme. Table 2 page 9 organizes the sizes and migration distances for the fragments of the standard included during electrophoresis. These values were used to construct the calibration curve m mentioned before (Figure 4).Figure 3 shows the agrees gel obtained by gel electrophoresis. Ta able 3 lists all sizes determined based on comparison with the calibration curve generated from migration standards (Figure 4). Sizes are noted for both the vector and the insert (4). Analysis of Reporter Gene Expression Investigation of gene regulation and interaction of environmental rabbinate a ND/or glucose with genotype required GAP+ cells to be spread on various plates, an d fluorescence to be observed over time.Table 4 summarizes the observations of the phenotype o f patches streaked onto AMP plates containing or lacking rabbinate and/ or glucose. Glowing patches suggest expression of the GAP gene. Observations show that the rabbinate sample pop site for the GAP insert fluoresced brightly as time went on. The sample with rabbinate and 0. 2 % glucose increasingly fluoresced over time, while plates higher in percentage glucose c imposition did not fluoresce. Cells that were GAP were also spread in order to serve as a surrogate et marker.These cells do not contain the gene for GAP, so they will not fluoresce under IV light . This gives a comparison, making it easier to determine if cells are expressing GAP fluoresce once or not page 10 DISCUSSION Regulation of Gene Expression: The samples that were grown with rabbinate, inclining, and varying amounts of glucose showed that the presence of glucose in a bacterium's surrounding environment NT can affect the ability of its rabbinate bad promoter. The plate with no glucose added flour cede brightly, while the plates with glucose added showed very little to no fluorescence.The only plate with glucose added that fluoresced in the end was the plate with the least glucose ad ded These results are due to the glucose inhibiting the rabbinate Oberon from trap inscribing the bad promoter DNA. When glucose is present in a bacterium, the cell metal likes the glucose instead of the rabbinate, and the rabbinate Oberon is not utilized. However, when the cell is lacking glucose, it reaches a state of â€Å"hunger† and begins producing cyclic adenosine Mephistopheles (CAMP). This reacts with the CAMP receptor protein (CROP), who chi allows the cell to use rabbinate to induce the transcription of the rabbinate bad prom otter.This promoter contains the genes Arab area , and award, which are part of the rabbinate Oberon. This system can only function if rabbinate is present in the cell; otherwise the gene arc will prevent the rabbinate Oberon from carrying out transcription by forming a â€Å"knot,† or loop in the DNA The rabbinate bad promoter reacts with the GAP gene to show when the Arabian SSE Oberon is in use and how strongly it is induced by rabbi nate (5). The plate with the least glucose added began to glow over time, as the cell be an using up the glucose in its environment by metabolize it for energy.It started to FL recurrences dully once the concentration of glucose was not high enough to fully repress the AR baboons Oberon, showing that there is a range of repression and induction, not just a state of † on† and â€Å"off' for page 11 these function. The more the bacteria used the glucose, the less of it was arrow ND to repress the Oberon, which is why its fluorescence strength grew over time. If the study WA s to be continued past the 96 hour mark, all of the plates would have eventually fluoresced as t hey used up their loses resources and began activating the rabbinate Oberon (4).

Sunday, November 10, 2019

Decadence in Death in Venice

The premise of decadence was tremendously popular in late 19th century European literature. In addition, the degeneracy of the individual and society at large was represented in numerous contemporary works by Mann. In Death in Venice, the theme of decadence caused by aestheticism appears through Gustav von Achenbach’s eccentric, specifically homoerotic, feelings towards a Polish boy named Tadzio. Although his feelings spring from a sound source, the boy’s aesthetic beauty, Aschenbach becomes decadent in how excessively zealous his feelings are, and his obsession ultimately leads to his literal and existential destruction.Thus exemplifying, as will be examined in the following, how aestheticism is closely related to, and indeed often the cause of, decadence. Although the narrative is about more complexities, the author’s use of such vivid descriptions suggest the physical, literal aspect of his writing is just as important to the meaning of the story. The first an d most obvious instance of aestheticism and decadence as correlating themes in this story is the title, Death in Venice. By shear nature the title relates the concepts of death and dying to the city of Venice, which implies that the location is where a death will occur.However, this is paralleled by the opening of the story when Mann drearily tells of Aschenbach’s stroll through Germany. â€Å"It was early May, and after several cold and clammy weeks, a mock summer had set it. The English Garden, though sprouting only tender leaves as yet, had been as muggy as in August. † In the reading of this passage it proves ironic that the title is Death in Venice as the protagonist seems to be dying in Munich: from his loss of creative ability, depletion of strength to the course of his walk ultimately leading him to a graveyard from which weakness forced him to catch a train home from.There lacks a sense of elegance with Mann’s description of aspects concerning Germany a nd a typical Aschenbach. This can be contrasted with the eloquent description given to Venice, † He saw it once more, that landing-place that takes the breath away, that amazing group of incredible structures the Republic set up to meet the awe-struck eye of the approaching seafarer: the airy splendour of the palace and Bridge of Sighs. † The obvious pleasure that Aschenbach feels as a result of the aesthetically pleasing city foreshadows how aestheticism will ultimately ead to his death and decay, important ideas within the context of decadence.This novella is a decadent meditation on the downfall of man. In an attempt to inspire his writing he decides to take a trip because he believes a change in scenery may add â€Å"those aspects of fiery and playful caprice† to his work. After arriving at his mountain cottage on an Adriatic island off the Istrian coast, he decided that the environment was â€Å"not conducive to making him feel that he had found what he was looking for. His descent into decadence begins after his arrival in Venice. Aesthetic and decadent traits are present within the context of the city – his loss of dignity for falling in love with a fourteen year old boy and subsequent degradation, also the idea that this boy prompts in Aschenbach a yearning for ideal aesthetic beauty. Immediately upon first sight, he became captivated by the boy’s aesthetically pleasing appearance, â€Å"Aschenbach was amazed to see that the boy was absolutely beautiful.His face, pale and of a graceful reserve, surrounded by honey-colored curls, with its straight nose, lovely lips, earnest expression, sweet and godly, all recalled Greek statues of the noblest era; but despite the pure and consummate form, his features exerted such a unique personal char, that the observer felt he had never encountered such perfection in nature or the arts. † Eventually his aesthetic attraction evolves to that of an emotional sort and he falls in love with him, although he at first denies this to himself, and his fixation eventually leads to his decadent demise.Therefore transitively, it could be understood that Aschenbach’s aestheticism directed him toward reckless decadence. However, as he walked down the crowded city streets scrutinizing his second destination he was repulsed. â€Å"The farther he went, the more tortured he was by the dreadful alliance of sirocco and sea air – a condition that both agitates and enervates. He sweated painfully. His eyes blurred, his chest tightened, he was feverish, the blood pounded in his temples†¦wiping his forehead, he realized he had to find a different vacation spot. This idea is a strong instance of aestheticism interacting with decadence in the sense that Venice originally represented to Aschenbach, beauty and renewal. His trip was supposed to refresh him as an author and an aging man but instead he reached a land that, although aesthetically pleasing, was dirt y, crowded, and repugnant. The last moments before Aschenbach slipped into complete decadence, his object of adoration was not enough for him to suffer for. He packed his bags and said his good-bye’s to both the boy and the city that had twice made him ill, prepared to leave.Misdirected baggage was the practical reason for his remaining in Venice but as Aschenbach gazed adoringly at his idol he admits to himself that it was Tadzio, the embodiment of youthful beauty, who had made it so difficult for him to leave. At this point in the narrative it becomes clear that quite literally Tadzio is a representative of the aesthetic muse that Aschenbach, being an artist, was searching for. From this point on he watches as Tadzio eats his meals, plays on the beach, and even goes so far as to trail his family on land and sea around Venice.While following him by way of gondola, Aschenbach addresses his aesthetic intoxication, â€Å"The adventurer felt as if his eyes were drinking in the voluptuousness, as if his ears were being wooed by such melodies; he also recalled that the city was ill, but concealing its illness out of greed, and he peered more wantonly after the gondola floating ahead of him. All that the confused man knew and desire was to keep ceaselessly pursuing the object that inflamed him. † It is interesting how in the midst of the description of Aschenbach’s therapeutic tryst, Mann shows Aschenbach’s thoughts coming back to the retched illness of Venice.This time he goes into more detail by addressing the greediness of the people, in order to not scare away tourists, to lie about the impending disease. This passage gives insight into more than just Aschenbach’s captivation by Venice but of the decadent trance he is put in by Tadzio’s exquisite appearance. It exemplifies Aschenbach’s knowledge of the danger of disease that is taking over the city but proves that he is so deeply enthralled by the beauty of Tadzio that his senses have become greedy and force him to remain in Venice at all costs, despite the dismay that will come to his physical being, to get their aesthetic fix.As disease and panic runs ramped, people flee and the city becomes emptier and emptier, Aschenbach feels relieved at the lessened chance of being caught adoring Tadzio from close and far and begins to disguise his passion less. He begins dressing extravagantly in an attempt to appear more youthful and attract the young boy. â€Å"Like any love, he wanted to please, and he was terrified that it might not be possible. He added cheerful, youthful touches to his suit, he wore jewels and used perfumes; several times a day e spent a long while getting dressed, and was adorned, excited, and anxious when he showed up for meals. Viewing the boy’s sweet, bewitching youth, he was sickened by his own aging body: the sight of his gray hair, his pinched features, mortified him, left him hopeless. He felt an urge for physica l revival and renewal; he frequented the hotel barber. † As Aschenbach changed his aesthetic appearance; donning jewels and perfumes, wearing makeup, dying his hair, he begins to recapture a youthful appearance.With his young and radiant appearance he now resembles the two men featured in earlier chapters of the novella; the stranger who had inspired a youthful craving in him in Germany, and the deplorably exuberant old man from the boat ride to Venice. Both men embody, at least in Aschenbach’s eyes, frivolous indulgence and fraudulent aesthetics. In particular, the moronic drunkard from the boat appeared to Aschenbach bizarre and obtrusive. â€Å"It was repulsive to see the state to which the dandified old man had been reduced by his sham association with youth. † However, now Aschenbach’s outlook, and appearance, has changed drastically.He is now concerned with making his own appearance more youthful and aesthetically pleasing, giving into decadence just like the foppish man he had once scorned. Thomas Mann’s particular use of detailed descriptions throughout the narrative makes obvious the literary importance of aestheticism. As the story progresses, Aschenbach becomes more and more concerned with aesthetics. The reader can see this from his original desire to a change of scenery, to his obsession with Tadzio’s appearance, and finally the changing of his own appearance. Eventually his concern with aesthetics becomes an obsession, which ultimately leads to his decadence.The change of scenery for something more aesthetically youthful and beautiful that Aschenbach had yearned for turned out to be the scene of a crowded, stifling city filled with cholera that eventually leads to his demise. Before this can occur however, he becomes internally decadent through his indulgence in Tadzio’s appearance. He then changes his appearance to please his idol which in turn corrupts himself by turning him into the type of decad ent man he once despised. These themes of aestheticism and decadence, not in juxtaposition but in duality, are used frequently by Mann throughout the novella.

Thursday, November 7, 2019

Response to Goodbye To Berlin essays

Response to Goodbye To Berlin essays I am a camera with its shutter open, quite passive, recording, not thinking (Isherwood 1). This phrase comes from the first page of Christopher Isherwoods most popular documentary styled novel, Goodbye to Berlin (1939). In this novel, Isherwood managed to establish a sort of matter-of-fact style by blending fact and fiction and achieving a naive, honest style for the narrator. The phrase I am a camera often appears in his work indicating his belief that a narrator should serve the role of a simple recording device (Caudwell 2). By achieving this, Isherwood provides the readers with an unsurpassed portrait of Berlin, a city in the process of internal decay, in the turbulent years of Hitler's rise in power. It is as if...Isherwood is masquerading as a war correspondent... (Piazza 2). Isherwood is the outsider looking in, observing a war (holocaust) in which he is not involved; but he does show glimpses and portraits of characters that have been affected by it. He immerses himsel f in the world of prostitutes, living almost anonymously in shabbily genteel and working class areas of the city and translating his experience of the demimonde image of what would eventually become the definitive portrait of pre-Hitler Germany, in Goodbye to Berlin (Summers 1). Because Isherwood brilliantly recorded what he saw, Goodbye to Berlin is a valuable social document, which provides an insight into Isherwoods handling the theme of war. In this research paper, the main concentration is set on the effects (private and social) the introduction of war, by the Nazism movement, has on the individual portraits (characters) of Berlin. Against the bleak but garnish background of a falling city, Sally Bowles, Peter and Otto, The Nowaks, The Landauers, and other Berlin denizens shuffle through their shabby cabaret choreography (Bryfonski, Harris 283). I...

Tuesday, November 5, 2019

Cómo se paga y costo de fianza migratoria en EE.UU.

Cà ³mo se paga y costo de fianza migratoria en EE.UU. Si un familiar o amigo es detenido por Inmigracià ³n es posible que el ICE o un juez fijen una fianza y pueda ser liberado mientras espera que se resuelva su caso. La fianza la puede pagar directamente un amigo o familiar del migrante detenido o, si nadie cercano tiene recursos econà ³micos para ello, se puede recurrir a una agencia autorizada. Pago de fianza por amigo o familiar del migrante detenido En estos casos, el amigo o familiar debe encontrase legalmente en Estados Unidos, prefirià ©ndose que sea ciudadano americano o un residente permanente legal. El pago debe hacerse por la totalidad de la cantidad fijada como fianza por el ICE o por el juez de corte migratoria. Se acepta pago en dinero en efectivo o con bonos del Tesoro de los Estados Unidos (bonds, notes). Para hacerse efectivo el pago es necesario cerrar previamente una cita por telà ©fono con la oficina local del ICE (appointment to pay the bond). El dà ­a de la cita acudir al lugar que se ha indicado y a la hora seà ±alada. Es muy importante que solo se presente un familiar o amigo del detenido que tenga estatus legal en Estados Unidos, ya que de encontrase en situacià ³n de indocumentado podrà ­a ser detenido. Adems, debe llevar un I.D. vlido, tipo licencia de manejar del estado en el que reside habitualmente, pasaporte estadounidense, tarjeta de residencia, etc. Asimismo, debe llevar la tarjeta original de su Nà ºmero del Seguro Social. No se admite llevar una copia de la misma. Finalmente, ante un oficial el amigo o familiar del migrante que deposita la fianza debe firmar los documentos I-305 - original del recibo de haber pagado la fianza- y el I-352 -copia del contrato de fianza. Estos documentos deben de guardarse porque ser necesario para recuperar la fianza cuando finalice el proceso en contra del migrante. ​Pago de fianza migratoria a travà ©s de una agencia autorizada En ocasiones es conveniente pagar a travà ©s de una agencia de fianzas migratorias, que se conocen en inglà ©s como bond agents. Por ejemplo, porque los familiares y amigos no tienen estatus legal o porque no tienen todo el dinero que piden de fianza para hacer frente a la misma. En estos casos puede decirse con carcter general que el familiar o amigo que solicita la colaboracià ³n de una agencia autorizada debe pagar entre el 15 y el 20 por ciento del total de la fianza en dinero en efectivo y garantizar el resto con un colateral, como puede ser con una propiedad, con la nà ³mina, el auto, etc. Es muy importante saber cunto se tiene que pagar, cul es el colateral y otras condiciones econà ³micas, como monto de tarifas no recuperables. Tambià ©n conviene tener en cuenta que los bond agents suelen cobrar como comisià ³n por sus servicios entre el 15% y el 20% del total de la fianza. Asimismo, algunos agentes exigen para pagar la fianza que una vez que son liberados los migrantes lleven unos grilletes de monitoreo electrà ³nico con un GPS incorporado para saber en todo momento dà ³nde se encuentra el migrante. Algunos agentes llegan a cobrar a los migrantes $420 por mes en concepto de arrendamiento por el grillete. Por estas razones es conveniente contactar con varias agencias y comparar las condiciones ofertadas por cada una de ellas y tener mucho cuidado con lo que se firma, particularmente si est en inglà ©s y no se entiende el compromiso que se adquiere.  ¿Cul es el monto de la fianza de migracià ³n? El costo de la fianza depende de varios factores, entre ellos: la gravedad de la acusacià ³n contra la persona extranjerasu historial delictivosi tiene familiares en los Estados Unidossu estatus migratorioposibilidades de desaparecer y no presentarse en las audiencias en la Corte de Inmigracià ³n En là ­neas generales hay dos tipos de fianzas migratorias: las fianzas conocidas como departure bonds se fijan a partir de $500, dependiendo del caso.los deliver bonds tienen un monto que puede ir desde los $1.500 hasta los $10.000 o ms. Segà ºn datos de la Executive Office of Immigration Review, en el aà ±o fiscal 2019 el monto medio de las fianzas migratorias es de $8.000. Con los deliver bonds el migrante queda en libertad mientras sigue en trmite su proceso de deportacià ³n. Si falta a alguna cita en corte, pierde el derecho a la libertad y todo el dinero entregado en concepto de fianza. Con los departure bonds el migrante se ha comprometido a abandonar EE.UU. en un plazo determinado y pagando à ©l o ella por los gastos de esta salida. El migrante queda libre despuà ©s de pagar esta fianza para poder arreglar sus asuntos antes de salir del paà ­s. Si no cumple con el plazo establecido, el migrante pierde el dinero de la fianza.  ¿Cunto se demora ICE en regresar el dinero de la fianza? Cuando el proceso que se sigue contra el migrante finaliza o cuando el migrante abandona EE.UU. se puede reclamar al gobierno que regrese el dinero depositado en concepto de deliver bond o departure bond. Segà ºn ICE, estn regresando la fianza en el plazo de un mes a partir de la fecha en la que se reclama su devolucià ³n. Sin embargo, datos publicados por la Universidad de Stanford y la Universidad de California, Davis, muestran que frecuentemente la demora es mucho mayor y que, como consecuencia de ello, ICE tiene bajo su custodia $204 millones en finanzas. Adems, 18.000 personas jams han reclamado la devolucià ³n de la fianza. La complicacià ³n del trmite impide que muchos migrantes puedan hacerlo sin encontrar ayuda legal cualificada. Pago de fianzas migratorias La posibilidad de pagar fianza y su monto lo establece ICE o un juez de Inmigracià ³nEl pago de la fianza para liberar a un migrante de su detencià ³n puede ser realizada por un familiar o amigo con estatus legal o recurrir a los servicios de un agente de fianzas.Si se utilizan los servicios de un agente, comparar condiciones entre varios, particularmente cunto tarde en depositar la fianza, porcentaje de su comisià ³n, tarifa no reembolsable, quà © pide de colateral y si exige que el migrante liberado utilice un grillete electrà ³nico.No es fcil el papeleo para reclamar a ICE que regrese el dinero de la fianza. Es muy comà ºn que se necesite recurrir a los servicios de un abogado o de una persona con conocimientos sobre este tipo de fianzas. Este es un artà ­culo informativo. No es asesorà ­a legal. Fuentes: Flynn, Meagan, ICE is holding $204 million in bond money, and some immigrants might never get it back The Washington Post. April, 26, 2019.https://www.washingtonpost.com/immigration/ice-is-holding-204-million-in-bond-money-and-some-immigrants-might-never-get-it-back/2019/04/26/dcaa69a0-5709-11e9-9136-f8e636f1f6df_story.html?utm_term.7a18f948b630

Sunday, November 3, 2019

Mobile Messaging Essay Example | Topics and Well Written Essays - 2000 words

Mobile Messaging - Essay Example Studies have shown that currently, about one billion people in the world use mobile messaging services. This has been projected to grow to about two billion users in the next three years (Khalaf, 2014). Some of the mobile messaging platforms that have been widely used in the world include Facebook, Whatsapp, Snapchat, Kik and Messenger. Different users have different preferences when it comes to the choice of platform to be used. However, cases of use of multiple platforms are also common. With the increase in the use of smartphones, mobile messaging has also grown rapidly. Smartphones war has also been caused by the rise and popularity of mobile messaging applications. Handset manufacturing companies such as Samsung and Apple have fought fiercely in popularizing their smartphones basically as a result of the popularity of mobile messaging. Due to this rapid rise in the use of mobile messaging services, a lot of studies have been carried out on this topic. The studies have shown that the growth or increased use of mobile messaging supported by platforms such as Facebook, Snapchat, Messenger and Kik has impacted heavily on the society. The impacts of mobile messaging on the society have been both positive and negative. One of the straight forward advantages of the use of mobile messaging is that it provides a form of communication in the society. Mobile messaging is real time. The messages or data that is sent from one mobile phone handset to another is received in real time. This therefore allow for sharing of information very fast and hence providing a channel of communication. The current world is a world where communication has become an important element in the day today life of an individual. Mobile messaging, unlike calls, is free and therefore allows for communication just by few keystrokes. This has allowed people in various regions of the world to

Thursday, October 31, 2019

Case study 2 Example | Topics and Well Written Essays - 250 words - 2

2 - Case Study Example The reason one experiences pain in the right upper quadrant is because of the position of the gallbladder, and what happens to the gall bladder whenever it is blocked by the gallstones. The gall bladder has the cystic duct through which bile flows into the duodenum. A blockade of this duct means that bile cannot pass through. It becomes concentrated in the gall bladder causing irritation and inflammation. This inflammation causes pain that radiates to the surrounding parts. This is why an individual with gallstones experiences pain in the right upper quadrant that may further extend to the back (Whitney & Pinna 565; Bluth & Benson 1). When one eats, more bile is produced from the liver, and this goes into the already inflamed gall bladder. The act of eating stimulates the gall bladder to contract and push the bile into the duodenum for the normal digestion process. Because of the existence of the gallstone on the cystic duct, the contraction causes pain (Crutchlow, Dudac, MacAvoy and Madara 213). If Martha gets lucky and the doctor finds out that the gallstones can be dislodged, they will pass through the duodenum. Here they can be dissolved using ursodeoxycholic acid, or can pass through the intestine (DeBruyne, Whitney & Pinna

Tuesday, October 29, 2019

Proposal document Essay Example | Topics and Well Written Essays - 250 words

Proposal document - Essay Example advancement of technology has brought with it additional academic pressures since professors expect that students can harness the information highway optimally to enhance the learning process and, concomitantly, expectations have risen insofar as quality of student output is concerned. Currently, there are four hundred public computer stations at the IUPUI library that provide access to campus electronic resources and to the internet, but they are not connected to the net either locally or wirelessly. In fact, it is not possible to download data on some computers in the library that are not equipped with the necessary software. The Policies: One of the variables that make things difficult is the set of policies imposed at the library. In the IUPUI library, there are four types of computers that students are permitted to use with added caveats, as listed below: The problem is the inability to download data using all computers available at the IUPUI library. This is a direct fallout of the library policy as detailed supra. Limiting the types of PCs that may be used for downloading data to only two categories, i.e., PCs with yellow tags and MAC computers, reduces the computer units usable in downloading certain software in furtherance of their assignments and projects. According to the Help Desk Supervisor, Adam, there are only eighty-six PCs on the third and fourth floors with yellow tags. Although MAC computers can also be used to download data, many students are not be able to use them due to their unfamiliarity with MAC computers. Even with the assumption that MAC computers are fully utilized, the paucity of units available is an impediment that is beyond the control of students needing access to PCs. Computer Information Technology (CIT) major students, like me, are left with no recourse but to purchase their own Laptop computers and bring them to the library, which is an undesirable and avoidable stop-gap measure. An analysis has been carried out by me to

Sunday, October 27, 2019

The Resource Based View Analysis

The Resource Based View Analysis This report reviews empirical studies of the resource-based view (RBV) and examines the benefits and limitations of RBV as the best strategy route in the developing a firms strategy. By having a clear and focused strategic intent, it mobilises an organisation towards achieving the desire position. Through analysing its internal and external environment using the resource based view and Porters industry analysis respectively, firm would be able to achieve sustainable competitive advantage. The key to a resource based view is through an understanding the relationships between resources, capabilities, competitive advantage, and economic rent. The RBV identified characteristics of advantage-creating resources such as value, rarity, imitability and Organisation (Clulow et al, 2007; Barney, 1991). In contrast, porters industry analysis focuses on lower cost and product differentiation in achieving sustainable competitive advantage. Despite the conflicting issues, the resource based view has examined issues and new directions that will help to clarify the value and boundaries of the RBV by integrating with Porters industry analysis. Porters framework and the RBV of the firm basically perceived the primary role of strategy as achieving a unique competitive advantage (Hax A. C. and Wilde II D. L., 2003). Thus, both frameworks can complement each other as they emphasise in different dimensions of strategy (Hax A. C. and Wilde II D. L., 2003). (200 Words) Introduction The resource based view of the firm (RBV) is one of the contemporary strategic management concepts to develop a firms strategy. The primary objective of this report is to accept or reject the contention that resource-based view analysis (RBV) has a strong relationship with firms performance in achieving a sustainable competitive advantage. This report reviews the literature on competitive advantage and firm performance. It is divided into five main components. The first section summarizes the literature on competitive advantage from two viewpoints, the Resource Based View (RBV) and Porters Industry Analysis (IA). The second section discusses on the strengths of the RBV in reviews with the literature on strategic intent, threshold resources, capabilities, competitive advantage, core competencies, sustainable competitive advantage and VRIO. The third section illustrates Porters IA in reviews with cost, differentiation, and market focus. The fourth section deliberates the criticisms of the RBV and illustrates how researchers have or have not overcome some of these boundaries. The fifth section is a review of an integration of the RBV and Porters IA in the proposed model of core competencies, competitive advantage and firm performance (Chabert J. M., 1998) (185 Words) The Resource Based View of the Firm Thompson et Al (2010) point out that RBVÂ  [1]Â  uses a companys VRIOÂ  [2]Â  strengths and competitive capabilities to deliver value to customers in way that rivals find it difficult to match. The RBV emphasises the internal capabilities of the organisation in formulating strategy to achieve a SCAÂ  [3]Â  in its markets and industries (Henry, 2008). It holds that firms can earn sustainable abnormal returns if and only they have superior resources and those resources are protected by some form of isolating mechanism preventing their diffusion throughout industry (Value Based Management.net, 2011). The Resourced Based View Assumptions The RBV of firms is based on two main assumptions involved resource diversity and resource immobility (Barney, 1991; Mata et al, 1995). According to Mata et al. (1995), resource diversity concerns whether different firms possess bundles of different resources and capabilities; while resource immobility refers to a resource is difficult to obtain by competitors because it is inelastic in supply or costly. These two assumptions can be used to determine whether an organisation is able to create a SCA by providing a framework for determining whether a process or technology provides a real advantage over the marketplace (Brown, 2007). Thus, the RBV tends to focus on the types of resources and the characteristics of these resources that make them strategically important, the dynamic capability perspective which focuses on how these resources need to change over time to maintain their market relevance (Powell, 2007). The RBV as the best strategy route in developing a firms strategy Today managers are moving manufacturing offshore to lower costs of labour, rationalising product lines to capture global scale economies, instituting quality circles and just in time production, and adopting Japanese human resource practices. It was believed that the application of concepts like strategic fit (between resources and opportunities), generic strategies (low cost, differentiation and market focus) and the strategy hierarchy (goals, strategies, and tactics) have often aided the process of CAÂ  [4]Â  (Hamel and Prahalad 1989; Andrews, 1971). Most companies have approached competitor analysis that focuses on the existing resources like human, technical and financial of present competitors. Whereas, the only threat those companies aware are those with the resources to erode margins and market share in the future. There are few Japanese companies possessed RBV, manufacturing volume or technical competence of U.S. and European leaders. For instance, Canons first halting step s in reprographics business looked pitifully small compared with the $4 billion Xerox powerhouse (Hamel and Prahalad 1989). Strategic Intent Strategic intent envisions a desired leadership position and establishes the criterion the organisation will use to chart its progress where Komatsu set out to encircle Caterpillar. The concept emphasises an active management process that involved focusing the organisations attention on the essence of winning, motivating people by communicating the value of the target, leaving rooms for individual and team contributions, sustaining enthusiasms by providing new operational definitions as circumstances change and using intent consistently to guide resource allocations (Hamel and Prahalad, 1989). Strategic intent captures the essence of winning. For example, the Apollo program where landing a man on the moon ahead of the Soviets was as competitively focused as Komatsus drive against Caterpillar. It is stable over time, in order to challenge global leadership; one of the most critical tasks is to lengthen the organisations attention span. It provides consistency to short term action, which leaving a room for reinterpretation as new opportunities emerge (Hamel and Prahalad, 1989). A firm is said to have a CA when the firm can produce more economically and higher customer satisfaction, and thus enjoy superior performance relative to its competitors (Barney, 1991; Peteraf, 1993). Whereas, Porter (1985) defined CA as the ability to earn returns on investment consistently above the average for the industry by focusing on the companys external competitive environment and how they position themselves against that structure (Halawi L. A., Aronson J. E, and McCarthy R. V., 2005). In contrast, the RBV of strategy points not to industry structure but to the unique cluster of RCÂ  [5]Â  that each organisation possesses (Henry, 2008; Collis and Montgomery 1995; Stalk et al, 1992). Firms Outperform and Maintain Competitive Advantage The Benefits of RBV RBV is best applied for the kind of assessment of a firms existing resource portfolio discussed by Barney (2001) or when exploiting the firms stock of resources to move into new product markets, as in the tradition of Penrose (1959) (Sheehan and Foss, 2007). There are two fundamental reasons for making the RC of the firm the foundation for its strategy. First, it provides the basic direction for a firms strategy and second, they are the primary source of profit for the firm. The RBV perceives the value derived from management skills, information capabilities, and administrative processes can also be regarded as scarce factors able to generate economic rents (Sheehan and Foss, 2007). The concept of a dynamic capability was developed to explain why some firms have been able to outperform their competitors over long periods of time and despite significant changes in the marketplace (Teece et al, 1997). Firms as bundle of Resources Threshold resources are defined as the unique combination of assets and capabilities within a firm that enable firms to develop and implement strategies to meet customers minimum requirements and to improve its overall performance (Scholes J. G., and Whittington, R., 2008). It can be classified as either tangible or intangible resources. Tangible resources refer to the physical assets that a firm possesses and can be characterised as physical resources. In order to add value, these physical resources must be capable to respond to marketplace changes. Intangible resources comprise of human and organisational capitals. It may be embedded in routines and practices that have developed over time within the organisation (Henry, 2008). It includes knowledge based economy, the tacit knowledge and specialist skills of many employees which are difficult for competitors to imitate (Henry, 2008). Nonaka and Takeuchi (1995) differentiate between knowledge that can be seen as tacit and explicit. An explicit knowledge or knowing about is shown through communication that can be readily transferred therefore it requires some form of protection like copyright. Whereas, tacit knowledge or know how cannot be codified and it is revealed through its application and acquired through practices such as beliefs and perspectives (Henry, 2008). RBV and Organisational learning The RBV stresses the significance of developing and enhancing those resources that are distinctive, in particular, distinctive capabilities (Olavarrieta and Ellinger, 1997). Ten3 Business e-Coach (2001) defined capabilities as the capacity for a set of resources to interactively perform a business process. Capabilities, are the type of resources that is a source to SCA because they are based on organisational routines and processes, which are socially complex, knowledge-based (explicit and tacit) and difficult to observe and imitate. A firm is able to possess dynamic and operational capabilities, where dynamic capabilities are defined as those processes that allowed the firm to change its resource base in some ways to meet the differences in strategic and competitive challenges (Zubac et al, 2010; Helfat et al, 2007). The concept of a dynamic capability was developed to explain why some firms have been able to outperform their competitors over long periods of time and despite significant changes in the marketplace (Teece et al, 1997). It is specific and identifiable processes involved conceptualisation, product development, strategic decision making and alliancing (Eisenhardt and Martin, 2000, p. 1105). Conversely, operational capability is the firms capacity to combine, assemble and deploy the firms assets using pre-determined activities, routines, processes and the skills of its employees to make products and services that are a source of potential profits to the firm available to its customers (Spanos and Lioukas, 2001). However a firm will usually focus on certain capabilities consistent with its strategy such as if a firm is pursuing a differentiation strategy, they would focus on new product development, whereas a firm which adopting low cost strategy would focus on improving manufacturing process efficiency (Henry, 2008). Capabilities, however, are not built in short term basis, they are dependent on a firms personnel, its knowledge and understanding of the marketplace and customers requirements and operations (Olavarrieta and Ellinger, 1997). The Competitive Advantage of RBV Competitive advantages and disadvantages in resources are equivalent to strengths and weaknesses respectively, which stimulate cost and differentiation advantages or disadvantages in competitive product markets (Valentin K. E., 2001). An understanding of industry structure guides managers toward productive possibilities for strategic action, which may include positioning the company to be better cope with the current competitive forces, anticipating and exploiting shifts in the forces, and shaping the balance of forces to create a new industry structure that is more favourable to the company (Porter, 2008). The CA gained by these key intangible assets and capabilities is then reflected in superior performance of the firm in financial terms such as higher profits, increased sales or market share (Clulow et al, 2007; Hunt and Morgan, 1995; Collis and Montgomery, 1995; Fahy, 2002; Wilcox-King and Zeithaml, 2001). The Competencies of an Organisations Henry (2008) evaluated competency as the internal capabilities that firms require in order to be able to compete in the marketplace. In addition, Zubac et al (2010) defined CCÂ  [6]Â  as the collective learning of individual members within the firm and their ability to work across organisational boundaries. Prahalad and Hamel (1990, p. 82) stated that: The skills that together constitute core competence must coalesce around individuals whose efforts are not so narrowly focused that they cannot recognise the opportunities for blending their functional expertise with those of others in new and interesting ways. Thus, a CC or strategic capability can be thought as a collection of features that a firm possesses which enable them to achieve CA. Honda and BMW are examples of the organisations that have achieved CC in a way they configure their value chain respectively (Henry, 2008). RBV and Sources of Sustainable Competitive Advantage (SCA) Barney (1991) suggested that there can be heterogeneity or firm-level differences among firms that allow some of them to SCA. Ten3 Business e-Coach (2001) describes SCA as the continued benefit when an organisation is implementing a value-creating strategy that is not being implemented by current or potential competitors and when these competitors are unable to imitate the benefits of this strategy. Therefore, the RBV emphasises strategic choice, changing the management of the firm with the important task of identifying, developing and deploying key resources to maximise returns (Powell, 2007). Bharadwaj et al. propose a framework of SCA for a firm is derived from the assets and capabilities of the firm. The extent of the service firms SCA is basically determined by the degree of imitability inherent in the firms resources. Kerin et al (1992) presented an integrative framework of the literature on first mover advantage, suggesting that the realisation of SCA, through market pioneering, is contingent on the resources that a firm possesses (Olavarrieta and Ellinger, 1997). Strategic resources and Superior performances As a source of CA, RC must have four attributes which is VRIO in order to outperform others. A resource must be valuable as it enables the firm to conceive or implement strategies that improve its efficiency and effectiveness through lower costs and incline of revenue (Ecofine, 2010). Substitutability refers that there must be no strategically equivalent valuable resources that can be exploited to implement the same strategies (12manage, 2008). For instance, Wal-Mart sells most of the same merchandise as its major competitors, but the effectiveness and innovation of its logistics system ensures that it is the market leader in its field. Wal-Marts valuable and imitability point-of-purchase inventory control systems and cross-docking distribution plants have resulted in competitive advantage relative to its major US competitor, K-Mart (Olavarrieta and Ellinger, 1997; Barney, 1995). Porters Framework Porters Industry Analysis There are three sources that is irreproducible such as market structure that limits entry, a companys history which by definition will require time to replicate and tacitness in relationships refers to the routines and behaviours which cannot be imitate since the organisations themselves are unsure how they work (Henry, A., 2008). Porters mentioned that there are only two generic studies to compete either through low cost or product differentiation that lead to superior performance (Hax A. C. and Wilde II D. L., 2003). To assist managers in understanding, improving, and implementing a low cost or differentiation strategy, Porter (1985) developed the value chain framework; it is a generic activity template that is used to decompose the firm into the individual activities it undertakes to create value for the customer (Sheehan and Foss, 2007). Economies of Scale Cost leadership is achieved through the aggressive pursuit of economies of scale, product and process simplification, and significant product market share that allows companies to exploit experience and learning effects (Hax A. C. and Wilde II D. L., 2003). Dell being one of the organisation are protected by scale economies in their direct-sales method, efficient lean-manufacturing approach, expertise in logistics and supply-chain management. Hence, these capabilities provide it with CA and which its competitive rivals have found difficult to imitate (Henry, 2008). Differentiation and Core Competencies A differentiation demand for creating a product that customer perceives as highly valuable and unique (Hax A. C. and Wilde II D. L., 2003). The first-mover advantage refers to firms which benefit from the learning and experience they acquire as a result of being first in the marketplace like Toyota has achieved CC in the production of petrol-and-electric hybrid cars (Henry, 2008). Hence, a CC should provide access to a wide variety of markets, make significant contribution to perceived customer benefits of the end products and difficult to imitate. Honda is one of the organisations that focuses on the technical excellence of 4-cycle engines, have enabled it to leverage its CC to compete in markets from motorcycles to automobiles to a broad range of gasoline-engine products (Grant, M. R., 2001). Market focus Strategy can be viewed as building defences against the competitive forces or finding a position in the industry where forces are weakest. For instance, Paccar, a firm with heavy-truck market, has chosen to focus on one group of customers that is owner-operators. They have customised every single part of the value chain to work well with the forces in its segment. Thus, Paccar has earned a long-run return on equity above 20 % (Porter, 2008). Criticisms RBV Implications The RBV of the firm is a contemporary theory that provides insights on both strategic and organizational issues. An often-recurring critique on the RBV is that its core logic contains circular reasoning in the specification of the relationship between rents and resources (Truijens, 2003). Foss (2000) argued that the VRIO attributes in the RBV that valuable and rare resources can be sources of SCA is tautological. RBV has little attention on the important issues of how resources can develop and change over time. Likewise, the dynamic role played by individuals within organisations is often assumed to be self-evident and therefore seldom addressed (Henry, 2008). Another critique is that it is not sufficient clear in the RBV on how resources contribute to firm-level value creation and that operationalisation is therefore difficult (Sheehan and Foss, 2007; Priem and Butler, 2001) The RBV emphasises on the role of human capital in the creation of CA, which at the same time caused issues for accountants in terms of total business and intangible asset valuation (Toms, 2010). Accountants similarly are concerned with controls which prevent misappropriation of resources that ultimately are shareholders property. Thus, a theory of value also needs to be one of accountability (Toms, 2010). Conclusion Activity drivers and resources share many similarities, both resources and drivers influence a firms cost and differentiation position, and both need managerial involvement in the sense that drivers must be made controllable, while resources must be organized (Sheehan and Foss, 2007). Although these frameworks have often been presented as conflicting views; they can contribute greatly to the development of a strong business strategy. Since they emphasised different dimensions of strategy, they can complement each other. By integrating these frameworks, it enables activity-based view solves implementation issues that are unresolved when using the RBV (Sheehan and Foss, 2007; Barney and Arikan, 2001). It enhances many of the individual weaknesses of the two views. The activity-based view is weak in its assumptions about factor markets, which would be addressed by the RBV (Sheehan and Foss, 2007; Teng and Cummings, 2002). Thus, Porters industry analysis remains crucial and the choice should not be seen as one of either but rather one of complementarity. (2371 Words)